• Thrombosis

    Paradigm staff have developed and executed numerous CME initiatives in thrombosis and anticoagulation. These include, but are not limited to, multiple satellite symposia in conjunction with the annual congresses of the American Society of Hematology (ASH), American College of Physicians, American College of Cardiology, and the American Heart Association; 1,500 CME-certified in-hospital Grand Rounds programs; and 25 live CME certified regional workshops.

UNCOVERING THE NUANCES OF ORAL ANTICOAGULATION FOR OPTIMAL MANAGEMENT OF HOSPITALIZED PATIENTS

During this CME-certified symposium, expert faculty will provide guidance - via didactic lecture and interactive case studies - on how to identify at-risk patients who are candidates for oral anticoagulation therapy in the hospital setting. Through the use of iPad technology to enhance the learning experience, participants will be provided with evidenced-based information allowing for differentiating among the oral anticoagulants, selecting the most appropriate oral anticoagulant for at-risk patients based on individual drug and patient characteristics; and understanding strategies for stopping and reinitiating anticoagulation in patients undergoing surgical procedures.

 

NONWARFARIN ORAL ANTICOAGULANTS (NOACS): THE CLINICAL PHARMACIST'S PERSPECTIVE

Few topics are as relevant - or of as intense interest - to contemporary pharmacy practice as the appropriate use of nonwarfarin oral anticoagulants (NOACs) approved by the FDA in January 2015. NOACs offer distinct advantages over warfarin; they have a rapid onset of action, more predictable pharmacologic profiles, and significantly reduced food and drug interactions. This activity offers education for clinical pharmacists on the latest evidence surrounding the different indications for NOACs, proper dosing strategies, management of bleeding, counseling patients on the safe use of NOACs (and how they differ from warfarin), managing and monitoring for food-drug and drug-drug interactions, and managing care transitions.

 

CONSIDERATIONS IN THE CLINICAL USE OF NON-WARFARIN ORAL ANTICOAGULATION IN THROMBOSIS

Nonwarfarin oral anticoagulants (NOACs) have emerged as key therapies to prevent and/or treat potentially deadly thrombotic conditions including stroke or systemic embolic events in patients with nonvalvular atrial fibrillation and venous thromboembolism. Although NOACs offer many advantages over conventional therapies, confusion over certain aspects of their safe and effective use in clinical practice persist. This educational activity will provide the latest data and recommendations in a case-based format to help guide the appropriate and confident use of NOACs in a variety of scenarios commonly encountered in clinical practice.

 

ANTICOAGULATION IN THE EMERGENCY DEPARTMENT: A CASE-BASED APPROACH TO MANAGING PATIENTS WITH VENOUS THROMBOEMBOLISM AND NONVALVULAR ATRIAL FIBRILLATION

This live, interactive continuing medical education program will review current evidence and strategies for applying the information to confidently make appropriate "real-time" patient-centered treatment decisions in the emergency department with regard to the use of oral anticoagulation, and in particular the nonwarfarin oral anticoagulants. Key information will be presented in the context of patient case scenarios with the opportunity for participants to have their questions addressed by faculty. Topics include red flags for recognition and efficient diagnosis of nonvalvular atrial fibrillation and venous thromboembolism in the emergency department, balanced risk assessment for thrombosis and bleeding, choosing among available oral anticoagulants, and new strategies for managing acute bleeding events.

 

OPTIMAL ANTICOAGULATION THERAPY: A PRESCRIPTION FOR IMPROVEMENT

Atrial fibrillation (AF) and venous thromboembolism (VTE) are among the most common and serious thromboembolic conditions seen in clinical practice. Despite the pharmacokinetic and pharmacodynamic advantages of the nonwarfarin oral anticoagulants over warfarin and their similar or better efficacy to reduce the risk of stroke in patients with nonvalvular AF and for recurrent VTE while reducing the risk for serious bleeding, these agents are still not appropriately used. In this CPE initiative, which includes a didactic lecture combined with a clinical case or cases pertinent to the role of the clinical pharmacist as a critical member of the anticoagulation management team, clinical pharmacy-driven strategies to improve processes of care and anticoagulation management (eg, integration of guidelines into clinical practice) are described.

 

CAPS: CREATING ANTICOAGULATION PLANS TO PREVENT STROKE IN PATIENTS WITH ATRIAL FIBRILLATION

This series of CME/CNE/CPE-certified in-hospital grand rounds included didactic lecture, real-world case study presentations, and a brief question-and-answer session with the expert faculty presenter.

 

RACE AGAINST THE CLOCK: OVERCOMING CHALLENGES IN THE MANAGEMENT OF ANTICOAGULANT-ASSOCIATED INTRACEREBRAL HEMORRHAGE

This audience-interactive CME satellite symposium was presented at the 81st Neurological Surgeons (AANS) Annual Scientific Meeting, April 27-May 1, 2013. An enduring peer-reviewed publication featured highlights of the live meeting and was distributed as a ride-along supplement in the Journal of Neurosurgery. The digital publication was located on the Paradigm website, www.paradigmmc.com.

 

STROKE PREVENTION IN PATIENTS WITH NONVALVULAR ATRIAL FIBRILLATION: INDIVIDUALIZED, PATIENT-FOCUSED TREATMENT

These series of grand rounds activities included didactic lecture, real-world case study presentations, and a brief question-and-answer session with the expert faculty presenter.

 

FRESH FROZEN PLASMA: CURRENT PRACTICES AND ALTERNATIVES

These CME-certified grand rounds activities targeted hospital-based HCPs, blood-bank directors, intensivists, critical care specialists, surgeons (ie, neurological, transplant, trauma, cardiovascular, general), clinical pathologists, emergency department physicians, cardiologists, pharmacy directors, and other HCPs involved in the decision to use blood products. Activities were designed to increase healthcare professionals' understanding of current uses of fresh frozen plasma and the associated safety and efficacy concerns while improving their awareness of newer plasma derivatives and their uses.

 

MANAGEMENT OF NONVALVULAR ATRIAL FIBRILLATION: MAKING THE DIAGNOSIS, CHOOSING THE APPROPRIATE ORAL ANTICOAGULANT

This series of grand rounds activities focused on developing strategies to screen patients for nonvalvular AF, evaluating the safety and efficacy data for the targeted oral anticoagulants compared with warfarin, and recognizing the cost of stroke and the importance of stroke prevention to patients with nonvalvular AF. Activities included didactic lecture, real-world case study presentations, and a question-and-answer session with the expert faculty presenter.

 

TARGETED ORAL ANTICOAGULATION: THE HOSPITALIST'S ROLE IN MANAGING STROKE PREVENTION IN ATRIAL FIBRILLATION

This series of live CME symposia was held in alignment with regular meetings of state/regional chapters of the Society of Hospital Medicine. They focused on the pharmacologic differences among the oral anticoagulants, the evidence for restarting anticoagulant therapy following a major bleeding event in patients with nonvalvular atrial fibrillation, and the importance of the transition of care for patients with nonvalvular AF to both the inpatient and outpatient settings.

 

CLARIFYING CONCERNS AND CLINICAL CONUNDRUMS: ENSURING APPROPRIATE USE OF TARGET-SPECIFIC ORAL ANTICOAGULANTS

This series of live CPE symposia was held in alignment with meetings of regional-, state-, and local-level chapters of professional pharmacy associations, including the ASHP, the AMCP, and institutional and state pharmacy associations. They focused on validated risk assessment tools to identify patients who may benefit from anticoagulation, selecting the most appropriate agent, and evidence-based strategies to ensure appropriate management of patients on target-specific oral anticoagulants.

 

MITIGATING STROKE RISK ACROSS THE CONTINUUM OF CARE: THE ROLE OF TARGETED ORAL ANTICOAGULANTS IN ATRIAL FIBRILLATION

This enduring on-demand CME webinar included didactic and case-based discussions presented in a roundtable format and involved experts from the specialties of cardiology, emergency medicine, primary care, and clinical pharmacy. The webinar was hosted on www.paradigmmc.com, and was promoted via several mechanisms, including a robust email campaign to Paradigm's internal database of learners and distribution through PeerAudience's OpenCME Network.

 

TARGETED ORAL ANTICOAGULATION IN THE EMERGENCY DEPARTMENT: KEY FACTORS IN STROKE PREVENTION IN ATRIAL FIBRILLATION

This live, interactive CME satellite symposium presented at ACEP14 included didactic lectures and in-depth moderated Q&A between attendees and faculty, and focused on stroke prevention in atrial fibrillation from an emergency department perspective. An enduring web monograph was developed from the proceedings and was accessible via the Paradigm website, www.paradigmmc.com, as well as via the University of Cincinnati's CME website, www.cme.uc.edu; and the myCME website, www.myCME.com.

 

TARGET-SPECIFIC ORAL ANTICOAGULATION: FOCUS ON VENOUS THROMBOEMBOLISM AND ATRIAL FIBRILLATION

This live, interactive CME satellite symposium presented at the American Heart Association (AHA) Scientific Sessions 2014 featured a moderated roundtable discussion among experts in thrombosis management and in-depth, moderated Q&A between attendees and faculty, and focused on optimal use of current and emerging oral anticoagulants for stroke prevention in atrial fibrillation and venous thromboembolism. An enduring CME/CPE on-demand video webinar developed from the proceedings of the live symposium is accessible via the Paradigm website, www.paradigmmc.com, Paradigm's cardiovascular-focused portal, and the myCME website, www.myCME.com.

 

ANSWERING THE CALL: THE ROLE OF HEALTH-SYSTEM PHARMACISTS TO IMPROVE USE OF TARGET-SPECIFIC ORAL ANTICOAGULANTS

This live, interactive CPE symposium presented at ASHP Midyear 2014 included didactic lectures and in-depth moderated Q&A between attendees and faculty, focused on optimal use of target-specific oral anticoagulant. An enduring web monograph developed from the proceedings of the live symposium was hosted on the Paradigm Medical Communications, LLC website (www.paradigmmc.com) and the Power-Pak C.E. website (www.powerpak.com).

 

NEW OPTIONS FOR ACUTE TREATMENT AND SECONDARY PREVENTION OF VENOUS THROMBOEMBOLISM: TRANSLATING DATA INTO CLINICAL PRACTICE

This series of CME/CPE/CNE-certified in-hospital grand rounds include didactic lecture, real-world case study presentations, and a brief question-and-answer session with the expert faculty presenter. This iniative also included visiting professor forums, additional guided discussions led by the expert faculty presenter at the grand rounds locations, designed to engage department heads, chief residents, and fellows from the target specialties at the host institution.

 

TARGET-SPECIFIC ORAL ANTICOAGULATION IN CLINICAL PRACTICE: BREAKING NEWS, CONTEMPORARY VIEWS

This live, interactive CME satellite symposium included didactic lectures, interactive patient case studies, and in-depth moderated Q&A between attendees and faculty, as well as patient education information and a prescribing pocket guide, presented at Internal Medicine 2015. A CME-certified on-demand video webinar developed from the proceedings includes the patient education information and downloadable version of the prescribing pocket guide. The enduring webinar will be accessible via the Paradigm website, www.paradigmmc.com, Paradigm's cardiovascular-focused portal, and the myCME website, www.myCME.com

 

HOSPITALISTS ON THE FRONTLINE: PREVENTING AND MANAGING THROMBOEMBOLIC EVENTS

This live, interactive CME satellite symposium, presented at Hospital Medicine 2015, included didactic lectures, in-depth moderated Q&A between attendees and faculty, and patient education resources. An enduring web monograph developed from the proceedings features the most clinically relevant content and additional resources such as patient education materials. The interactive CME-certified web monograph is accessible via the Paradigm website, www.paradigmmc.com, the HQF website, and the website for The Hospitalist, www.the-hospitalist.org.

 

KEY UPDATES IN MANAGING ORAL ANTICOAGULATION AND ITS REVERSAL

This series of text- and audio-video-enabled CME/CPE-certified quarterly web newsletters will report on the latest developments in the field of thrombosis management, featuring summaries of important presentations at major medical conferences and embedded interviews with leading clinicians, researchers, and opinion leaders in the field of anticoagulation. These web newsletters will be accessible via the Paradigm website, www.paradigmmc.com, and the Hospital Quality Foundation (HQF) website, www.hospitalqualityfoundation.org and will be distributed quarterly by Paradigm, HQF, and Elsevier.

 

ANTICOAGULATION THERAPY IN PRIMARY CARE: KEEPING YOUR FINGER ON THE PULSE OF CURRENT CLINICAL RECOMMENDATIONS

Atrial fibrillation (AF) is the most common and important cardiac arrhythmia encountered in clinical practice. Even with the availability in recent years of 4 non-warfarin oral anticoagulants (NOACs), many at-risk patients are not assessed or treated appropriately due in part to confusion about where these agents fit in clinical practice. Due to pharmacodynamic and pharmacokinetic differences among the agents, patient-specific risk factors such as renal clearance must be taken into consideration when prescribing an NOAC. This activity has been designed to help primary care clinicians identify at-risk patients with AF, conduct an evidence-based work-up, and develop individualized treatment plans that appropriately utilize newer therapies when indicated.